Haemorrhoids and other anal symptoms: sorting them out instead of enduring them
Everyone has haemorrhoids. Not everyone has haemorrhoidal disease. And the most important rule for anal symptoms is not a treatment rule but a thinking rule: look first, name second.
All articles from the gut cluster
Hardly any topic is carried alone for as long as this one. And hardly any is sorted out as quickly. An anal examination takes a few minutes. The waiting often takes years.
You are sitting on the toilet and you see blood on the paper. Not much. A streak, bright red.
Your head does two things in that second. It says: those will be haemorrhoids. And it says: what if they are not. Then comes the third thought, and that one is the most expensive. It says: I am certainly not going to a doctor with this.
Many people know this pattern. Buy an ointment, wait, it gets better, it comes back. At some point a state of affairs has settled in that nobody talks about, even though it shapes sitting, sport and sometimes closeness too.
This text is not a treatment manual, it is an aid to sorting things out. Because with anal symptoms the medical work lies before the treatment: in naming cleanly what is actually there.
What is waiting for you here
- Why haemorrhoids are an organ, not a disease
- The sentence about bleeding that is not negotiable
- How reliable the attribution really is
- Fissure, thrombosis, fistula, skin tag, eczema, prolapse and the rare exceptions
- Grades 1 to 4 and what they steer
- Ointments, ligation, surgery with numbers
- The causal chain and how well it is supported
- Pregnancy and the postpartum period
- What everyday life can contribute
- Why shame costs so much time
Blood at the anus is never assigned to haemorrhoids without an examination.
The same bleeding can come from an anal fissure, from a fistula, from an inflammatory bowel disease, from a polyp or from a tumour. On the paper it looks far too similar to be told apart there.
The German S3 guideline puts it like this: pain points to other causes, for example fissure, abscess or thrombosis. Peranal bleeding must be investigated, and a bleeding source higher up should be ruled out. The same guideline adds: depending on age the adenoma rate reaches up to 20 percent, the rate of colorectal carcinomas is around 1 percent, and most studies recommend an endoscopic examination for transanal bleeding from the age of 40. That age figure concerns the question of how far up someone looks, not the question of whether anyone looks at all. The anal examination itself applies at every age, and as you will see further down, bleeding in people under 50 is particularly often assigned to haemorrhoids too quickly. Whether an endoscopy is needed in addition is decided by the examining practice on the basis of findings, symptoms and history, not by the year of birth alone.
The reassurance belongs right next to it. In a systematic review from general practice, the pooled positive predictive value of rectal bleeding for bowel cancer was 8.1 percent from age 50, with a confidence interval of 6 to 11 percent and clearly differing values across the individual studies, there from 2.2 to 16 percent. Eight in a hundred, not ninety in a hundred. The large majority of bleeding does not come from cancer. And eight in a hundred is still not nothing.
Joos AK, Jongen J. S3 guideline on haemorrhoidal disease. coloproctology. 2021. AWMF 081/007. DOI: 10.1007/s00053-021-00555-z [Guideline] · Astin M et al. Br J Gen Pract. 2011;61(586):e231-e243. PMID: 21619747 · DOI: 10.3399/bjgp11X572427 [Systematic Review]- Blood in the stool or at the anus, any amount, any colour, any age
- Black, sticky, tarry stool
- Unintended weight loss
- Fever
- Night time symptoms that wake you from sleep
- Vomiting or difficulty swallowing
- A new, persistent change in bowel habit from about age 45 to 50
- Anaemia in the laboratory, even without visible bleeding
- Bowel cancer or an inflammatory bowel disease in the family
- A sudden, very painful lump at the anus, because the course can still be shortened then
These signs are not a reason to panic, they are a reason for an appointment. Three exceptions do not belong in an appointment diary, though. With heavy or ongoing bleeding, especially together with pallor, a racing heart, dizziness or weakness, with black tarry stool, and with a painful swelling at the anus together with fever or shivering, you call the emergency number 112, which works in Germany and across the European Union, or you go to the nearest emergency department, at night and at the weekend too. Outside consultation hours the German out of hours medical service can otherwise be reached on 116 117. Nothing in this article replaces a recommended colonoscopy or proctoscopy.
Every person has haemorrhoids. Not everyone has a disease.
Let us start with the misunderstanding that underlies all the others. Haemorrhoids are not a disease you catch. They are an organ you have had since birth.
In the uppermost part of the anal canal sits a ring shaped vascular cushion, the corpus cavernosum recti. Not a venous plexus in the sense of varicose veins, but an arteriovenous cushion, a tissue that can fill with blood and empty again.
Picture a soft sealing collar. The sphincter provides the coarse closure, the cushion the fine one. Without it you would not reliably know whether air, liquid or solid stool is waiting down there. The German S3 guideline writes that these cushions play an important role for fine continence. That is why no established procedure aims to remove this cushion completely. Surgery too takes away only the prolapsed parts and leaves the fine seal standing as far as possible.
W. H. F. Thomson examined the anal canal in 1975 anatomically and clinically at the same time.
He described specialised submucosal cushions that line the anal canal, and argued that haemorrhoids in the sense of a disease are nothing other than their downward displacement.
For you that means: the question is never whether you have haemorrhoids, but whether they have changed and whether they are causing you symptoms.
Thomson WH. The nature of haemorrhoids. Br J Surg. 1975;62(7):542-552. PMID: 1174785 · DOI: 10.1002/bjs.1800620710 [Anatomical and clinical study]When does this turn into a disease? When three things come together: the vascular channels widen, the cushion slides downwards, and the supporting connective tissue loses its hold. This three part account comes from a review by Varut Lohsiriwat. It explains why purely vascular agents reach a limit: when the anchoring rope gives way, making the balloon smaller helps little.
From the normal cushion to haemorrhoidal disease
- Starting state. An arteriovenous cushion in the upper anal canal that takes care of the fine seal.
- Increased filling. The venous outflow runs through the internal sphincter. If pressure rises, more blood backs up in the cushion.
- Vascular widening. The vascular channels widen permanently, the tissue grows larger and becomes more vulnerable at the surface.
- Loss of anchoring. The supporting connective tissue changes, the cushion shifts downwards.
- Visible consequence. Bleeding on contact, weeping, a feeling of something being there, and with stronger displacement a prolapse on straining.
The first three steps are well described. The fourth is mechanistically plausible, human studies with hard endpoints are missing.
A Viennese team around Stefan Riss examined 976 people from the Austrian screening programme with colonoscopy and a proctological examination.
38.93 percent had haemorrhoids. Of those, 55.26 percent had no symptoms at all. Distribution: grade 1 in 72.89 percent, grade 2 in 18.42, grade 3 in 8.16, grade 4 in 0.53 percent. Body mass index was an independent risk factor, one point more corresponded to 3.5 percent more risk.
For you that means: the finding alone is not a diagnosis. It says about as much as the sentence that you have moles.
Riss S, Weiser FA, Schwameis K et al. The prevalence of hemorrhoids in adults. Int J Colorectal Dis. 2012;27(2):215-220. PMID: 21932016 · DOI: 10.1007/s00384-011-1316-3 [Cross sectional study, n=976]For Germany the S3 guideline gives an order of magnitude: about 4 percent seek medical help for this, which is around 3.3 million treatment cases per year, of which about 1.5 percent are operated on. In the same chapter it writes that good valid studies on epidemiology are not available. An estimate, not a measurement.
Inside and outside are two different stories
One anatomical border makes the topic understandable in the first place: the dentate line. Above it lies mucosa that reports pressure and stretch but no sharp pain. That is where the haemorrhoidal cushion sits. Below it the anoderm begins, a very sensitive skin. There you feel an injury immediately and precisely.
The most common thinking error goes: pain equals bad haemorrhoids.
It is rather the other way round. Internal haemorrhoids bleed, weep, press and itch, but they usually do not really hurt. Strong pain therefore does not speak for severe haemorrhoidal disease, it speaks for something else. That is exactly what the guideline says. And now you know why the next section is the most important one.
Blood at the anus, and why it is never assigned without a look
How often have you heard that bright red blood is harmless and dark blood is dangerous? I have deliberately left that rule of thumb out. The data base is a single observational study, and a sentence about blood colour would make bright blood look like an all clear.
The list of possible bleeding sources is short enough to remember and long enough to forbid guessing: haemorrhoids, anal fissure, anal fistula and abscess, inflammatory bowel disease, polyps, colorectal carcinoma, diverticular bleeding, rectal prolapse and solitary rectal ulcer.
Two of them I only touch on. In Crohn's disease and ulcerative colitis bleeding belongs to the picture, more in the article on inflammatory bowel disease. Diverticula usually bleed suddenly and painlessly, see diverticula and diverticulitis.
How reliable is the attribution actually?
Now an uncomfortable study. I show it because it delivers an argument for the examination and not against anybody.
A group around Alexis Grucela at Mount Sinai showed 198 doctors seven images of benign anal findings and asked them to write down the diagnosis.
The accuracy rate was 53.5 percent. Surgeons reached 70.4 percent, all other specialties stayed below 50 percent. Only 4.1 percent had all seven right, 20.2 percent had all seven wrong. The findings recognised least often were, of all things, the haemorrhoidal ones. Years in the profession changed nothing about this.
For you this does not mean that doctors work badly, it means that anal findings are hard to tell apart from an image.
And because the question suggests itself: I am not a coloproctologist. In this study my own specialty falls into the half that stays below 50 percent. That is exactly why my role in this topic is a modest one: classify cleanly, do not miss the red flags, and pass people on in good time to the colleagues who see these findings every day.
Grucela A, Salinas H, Khaitov S et al. Dis Colon Rectum. 2010;53(1):47-52. PMID: 20010350 · DOI: 10.1007/DCR.0b013e3181bbfc89 [Prospective diagnostic accuracy study, n=198]A fair limitation and a constructive flip side belong with this. The limitation: these were photographs, not examinations. With history, palpation and a proctoscope the accuracy rate looks better.
The flip side comes from Thessaloniki: 36 randomised medical students. Those who had attended a coloproctology clinic recognised 80.6 percent of the findings correctly, the comparison group 43.1 percent. Spanos CP et al. BMC Surg. 2014;14:95. PMID: 25410432 · DOI: 10.1186/1471-2482-14-95 [RCT, n=36]. The poor recognition rate is not a law of nature, it is a question of practice.
The sentence that applies especially to young people
But I am still young. That sentence costs the most time.
Two New York centres reviewed all 180 people under 50 over 16 years who were operated on for bowel cancer, mean age 41.4 years.
94 percent had symptoms, and the most common symptom at 59 percent was bleeding. The authors write explicitly that the workup was frequently delayed and that the bleeding had often been assigned to haemorrhoids beforehand. 53 percent already had stage 3 or 4, only 8 percent had a first degree relative with bowel cancer.
For you that means: young age and an unremarkable family history change the probability, not the need to take a look once.
Myers EA, Feingold DL, Forde KA et al. World J Gastroenterol. 2013;19(34):5651-5657. PMID: 24039357 · DOI: 10.3748/wjg.v19.i34.5651 [Cohort, n=180]This work is retrospective and allows no risk estimate, it describes a pattern. It matches what the German S3 guideline writes about endoscopic investigation from the age of 40.
What a proper basic examination is
So that you know what you are getting into: the basic diagnostic work consists of conversation, inspection, digital rectal examination and proctoscopy, supplemented by rectoscopy when there is bleeding. That takes a few minutes. These examinations belong in a general practice, a coloproctology practice, a surgical practice or a gastroenterology practice. I describe them here so that you know what to expect, not as an offer. And I am not writing this text to frighten you: the large majority of what is found here is benign. In a worldwide survey of 1005 surgeons, 92.9 percent named the history, 91.2 percent the inspection and 91.1 percent the digital rectal examination. Standard, not exception.
Whether a colonoscopy makes sense in addition depends on age, symptoms and history. What awaits you there is described in the article on bowel cancer screening and colonoscopy. Here only this applies: if it has been recommended, this article does not replace it.
The diagnosis of haemorrhoids is an examination result, not an assumption. Anyone who states it without an examination is only saying what is statistically most common.
The look alikes, and how you tell them apart
This is, in my view, the most frequent gap in patient facing texts on this topic.
Many of them list other causes. How to tell them apart is written down less often. Yet the distinguishing feature is often simple: pain speaks against haemorrhoids. So I am trying it here, with the explicit limitation that a table does not replace an examination. It is meant to help you sort your symptoms.
Eight findings that are regularly confused with haemorrhoids. The table below tells you how to tell them apart
Anal fissure
pain leadsPerianal venous thrombosis
suddenFistula and abscess
discharge, feverAnal skin tags
usually harmlessAnal eczema, pruritus ani
itching leadsRectal prolapse
ring shapedAnal condylomata
nodules, itchingAnal carcinoma
does not recedeMemory aids, not anatomical depictions. The assignment is made by inspection, palpation and proctoscopy.
| Finding | Leading symptom | Character of pain | Bleeding pattern |
|---|---|---|---|
| Haemorrhoidal disease | Bleeding, weeping, feeling of something being there | Usually no real pain, more a pressure. Pain only with thrombosis or strangulation | Bright red, dripping or lying on the stool, often painless |
| Anal fissure | Pain during the bowel movement | Sharp and cutting during passage, then hours of burning | Little, bright red, streaked on the paper |
| Perianal venous thrombosis | Sudden taut lump at the anal margin | Constant pain, tender to touch, independent of bowel movements, onset within hours | Usually none, occasionally on spontaneous opening |
| Anal fistula and abscess | Swelling, discharge, feeling unwell | Throbbing, increasing, also at night, often fever | Pus or bloody discharge rather than pure bleeding |
| Anal skin tags | Soft flap of skin | None, at most a raw feeling when irritated | None |
| Anal eczema, pruritus ani | Itching and burning, stronger at night | Burning and soreness, no pain on passage | At most pinpoint from scratching |
| Rectal prolapse | Ring shaped protrusion | Little pain, but pressure and stool smearing | Mucous, partly bloody, with weeping |
| Anal condylomata (genital warts, HPV) | Soft, cauliflower like nodules | Usually no pain, more itching and a raw feeling | Pinpoint when irritated |
| Anal carcinoma | Lump, ulcer or induration that does not recede over weeks | Can be almost painless for a long time, later constant pain and an urge to pass stool | Repeatedly bloody, often with weeping or discharge |
Anal fissure: the tear that holds itself open
The fissure is the most important look alike, because it needs its own treatment.
A small tear in the anoderm triggers pain. The pain can make the internal sphincter cramp, and that cramping can worsen the blood supply exactly where the tear is supposed to close. A circle that carries itself. This is how we explain today why a fissure becomes chronic. It is a well supported model, not a proven sequence. The trigger is often very hard stool, sometimes the opposite, namely persistent diarrhoea.
Richard Nelson and colleagues pooled 75 randomised studies with 5031 participants and 17 substances for Cochrane.
Nitroglycerin ointment was marginally, but statistically robustly, superior to placebo: healing in 48.9 versus 35.5 percent, and in about half of those who initially became free of the tear it later returned. Botulinum toxin, nifedipine and diltiazem were equivalent in the same analysis, with fewer side effects. No drug treatment reached the success rate of surgical sphincterotomy, but none of them carried a risk of incontinence either.
For you that means: there are measurable drug options. Surgery is more successful, but it costs sphincter.
Nelson RL, Thomas K, Morgan J, Jones A. Cochrane Database Syst Rev. 2012;2012(2):CD003431. PMID: 22336789 · DOI: 10.1002/14651858.CD003431.pub3 [Systematic Review]The framing belongs with this, and it matters more to me than the percentages. All of these substances are prescription only. In Germany, nitroglycerin ointment is licensed for pain relief in chronic anal fissure, so the healing figures come from studies and sit next to that indication. Botulinum toxin, nifedipine and diltiazem are not licensed for the fissure, their use would be off label, with everything that goes with it: a separate medical explanation, no automatic reimbursement, greater medical responsibility.
And the risk side belongs with it just as much. Nitroglycerin frequently causes headaches and must not be used together with erectile dysfunction drugs of the sildenafil, tadalafil or vardenafil type, because blood pressure can then fall dangerously. After botulinum toxin, fine continence can be reduced temporarily, meaning control over wind. Nifedipine and diltiazem as an ointment can cause headache and skin irritation. I deliberately give no dosages here. That belongs in the hands of the treating practice, which knows your other medication.
The basis nevertheless remains stool consistency, because a tear closes poorly if something hard tears it open again every morning.
Perianal venous thrombosis: the lump that is there overnight
This is the finding that most often sends people into panic and least often brings them in quickly enough. Typical: sudden onset after straining, heavy lifting or long sitting, a taut bluish lump at the anal margin, pain even without a bowel movement.
A team around Jose Greenspon in Washington reviewed 231 people with a thrombosed external haemorrhoid, about half treated conservatively, about half by removal of the clot.
The time to becoming symptom free was 24 days conservatively versus 3.9 days after the procedure. The recurrence rate was 25.4 versus 6.3 percent. 44.5 percent had already had such a thrombosis before.
For you that means: whoever comes in the first days has a real choice. Whoever waits three weeks has usually already sat out the time.
Greenspon J, Williams SB, Young HA, Orkin BA. Dis Colon Rectum. 2004;47(9):1493-1498. PMID: 15486746 · DOI: 10.1007/s10350-004-0607-y [Cohort, n=231]The work is retrospective, and those with more pain were operated on more often. The time figures are therefore not a causal statement.
One distinction that rarely appears in patient facing texts: a perianal venous thrombosis on the outside is something different from an acute haemorrhoidal thrombosis with strangulated prolapse. For the second, the German S3 guideline calls for a primarily conservative approach in recommendation 46, because removing too much anoderm can bring about a narrowing of the anal canal that is hard to undo.
People really do search for instructions on opening such a lump themselves. I advise against this explicitly. The region is rich in nerves, rich in germs and hard to see, and tissue lost there does not grow back.
Anal fistula and perianal abscess: the surgical domain
When the pain throbs, increases over days and fever joins in, this is no longer a haemorrhoidal topic. An abscess is a collection of pus that has to be drained, a fistula is a tract from which discharge keeps coming. Both belong in a timely surgical assessment. Anal fistulas are common in Crohn's disease and sometimes the first sign, more on that under inflammatory bowel disease.
Anal skin tags: the most common misreading of all
Many people tell me they can feel their haemorrhoids. Mostly they are feeling a skin tag: a soft flap of skin at the anal margin, not pushable back inside, does not bleed, does not hurt. A reason to treat arises only when it makes cleaning so difficult that eczema develops. Otherwise it is a cosmetic finding, and procedures in this place have consequences.
Anal eczema and pruritus ani: the itch with many fathers
Itching at the anus, stronger at night than by day, is one of the most tormenting and most belatedly presented symptoms of all.
Manoharan Swamiappan summarised the state of knowledge on anogenital itching in 2016.
The skin of this region reacts particularly sensitively to soaps, fragrances, friction and a lack of ventilation. The range of causes stretches from infections and parasites through allergic skin reactions to underlying anorectal conditions and systemic causes. The paper warns explicitly against self treatment with steroid containing combination preparations, with the consequences of skin thinning, stretch marks and a masked fungal infection.
For you that means: when it itches, the first question is not which ointment, but what is keeping the itch going.
Swamiappan M. Anogenital Pruritus: An Overview. J Clin Diagn Res. 2016;10(4):WE01-WE03. PMID: 27190932 · DOI: 10.7860/JCDR/2016/18440.7703 [Mechanism Review]The circle usually looks like this: something irritates, you scratch, a preparation calms it briefly, the trigger stays. That is why the search for the cause comes before the preparation.
Rectal prolapse: the ring that gets confused with grade 4
If something ring shaped pushes outwards on straining and the folds run in circles around the centre, this is more likely a prolapse of mucosa or bowel wall. With grade 4, by contrast, several separate cushions lie outside with normal skin between them. The difference leads to completely different procedures. How pelvic floor and nervous system interact is touched on in the article on the gut brain axis.
Anal carcinoma, condylomata and infections: the rare ones that must not be missing
Two findings belong on this list, even though they are rare. There is a tumour of its own at the anus, the anal carcinoma, and at the beginning it can look like a skin tag, a fissure or a haemorrhoid. And there are anal condylomata, that is genital warts, caused by human papillomaviruses, out of which a precancerous change can develop over years. Both are one more reason why a change at the anus that is no better after two to three weeks belongs to be looked at, rather than treated further.
Anyone with a known HPV infection, anyone who is immunosuppressed, lives with HIV or has a history of cervical dysplasia should take this particularly seriously. The NCCN guideline on anal carcinoma records that this condition is treated across disciplines, in oncology, radiotherapy and surgery. I describe it here not as an offer, but so that you know it exists. A case report in the Qatar Medical Journal describes exactly this mix up and closes with the recommendation that symptoms which look like haemorrhoids, as well as rectal bleeding or a palpable lump, justify a physical examination and a prompt referral to gastroenterology or coloproctology. The authors themselves call the link between the mix up and delayed presentation anecdotal. A case report can show that something occurs, it cannot establish how often. Benson AB et al. J Natl Compr Canc Netw. 2023;21(6):653-677. PMID: 37308125 · DOI: 10.6004/jnccn.2023.0030 [Guideline] · English K et al. Qatar Med J. 2024;2024(1):7. PMID: 38362253 · DOI: 10.5339/qmj.2024.7 [Case report, single case]
A third point belongs alongside: infections transmitted during sex can also cause pain, bleeding, discharge or itching at the anus, for example an inflammation of the rectum caused by gonococci, chlamydia, syphilis or herpes viruses. This is not a question of how someone lives, it is a question of what is actually looked for. Without a history and a swab, something like this is not found.
The question is not: do I have haemorrhoids or something bad?
It is: which of these findings is it, and which of them needs which answer? Almost all of them are benign and treatable. That is exactly why the one look that finds the rare exception is worth it. For all of them the same first step applies: have someone take a proper look once.
Grades 1 to 4, and what they really steer
There is a number in the report, and many people read it like a school grade. It is not that. The classification goes back to the surgeon John Goligher and describes only one thing: how far the cushion steps outwards.
| Grade | What is visible | Frequency in the cohort | What usually follows from it |
|---|---|---|---|
| Grade 1 | Visible only in the proctoscope, enlarged, does not step forward | 72.89 percent | Stool regulation, sclerotherapy if needed |
| Grade 2 | Steps forward on straining, goes back on its own | 18.42 percent | Rubber band ligation as the procedure of choice |
| Grade 3 | Has to be pushed back with the finger | 8.16 percent | Ligation possible, surgery superior in the long run |
| Grade 4 | Lies permanently outside | 0.53 percent | Mostly surgical |
The German S3 guideline places two sentences beside this that often get lost in everyday practice. First: the transitions between stages are fluid. Second: symptoms need not correlate with size or prolapse. That explains two familiar experiences. A grade 1 can bleed, weep and shape everyday life. A grade 3 can be almost free of symptoms. The grade describes anatomy, not suffering.
What is the classification for, then? It steers the choice of procedure. In a survey of 1005 surgeons from 103 countries, 91.9 percent used four grades, and for 76.3 percent the grade was the single most important factor. Conservative treatment as first choice: at grade 1 in 92.5 percent, at grade 2 in 72.4, at grade 3 in 47.3 percent. At grade 4, 77.6 percent chose surgery first. Samalavicius NE et al. Colorectal Dis. 2024;26(10):1797-1804. PMID: 39169548 · DOI: 10.1111/codi.17140 [Survey of surgeons, n=1005]
The conservative basis is not a side note. For most grades it is the regular first step.
A high grade is not bad news about you, it is information about the path.
And a low grade is no reason to put up with symptoms. If grade 1 bothers you, that is worth treating. If grade 3 does not bother you, it is not automatically in need of treatment. And now you know why the guideline leaves symptom free findings alone.
The treatment paths, from conservative to surgical
Do you know the feeling that everyone recommends something to you and nobody says what it costs? That is why I go through the steps in order, with numbers on benefit, recurrence and price. Orientation from the literature, not prescriptions.
Step 1: stool consistency, the supported basis
Pablo Alonso-Coello and colleagues pooled seven randomised studies with 378 participants.
The risk of persisting symptoms fell by 53 percent (RR 0.47; 0.32 to 0.68), the risk of bleeding by 50 percent (RR 0.50; 0.28 to 0.89); in the parallel publication RR 0.53 (0.38 to 0.73). For prolapse, pain and itching, by contrast, the pooled results were compatible with a null effect (prolapse RR 0.79; 0.37 to 1.67). The authors explicitly name possible publication bias and moderate study quality.
For you that means: soft stool may clearly reduce symptoms and bleeding. It does not push a prolapsed cushion back.
Alonso-Coello P, Guyatt G, Heels-Ansdell D et al. Cochrane Database Syst Rev. 2005;(4):CD004649. PMID: 16235372 · DOI: 10.1002/14651858.CD004649.pub2 · Alonso-Coello P et al. Am J Gastroenterol. 2006;101(1):181-188. PMID: 16405552 · DOI: 10.1111/j.1572-0241.2005.00359.x [Systematic Review]The German S3 guideline names Plantago ovata and psyllium in recommendation 7 with grade B. How much fibre makes sense and why it can cause bloating at the start is described in the article fibre myths. Four things belong with this. Start slowly. Always take it with plenty of fluid, because bulking agents can clump in the oesophagus or the bowel without water. Do not use it with a known narrowing in the bowel, with suspected bowel obstruction or with swallowing difficulties, and clarify it medically beforehand if you have an existing bowel condition. And keep a gap of about half an hour to an hour from other medicines, because their absorption can otherwise be reduced. With diabetes, adjusting the medication belongs to the treating practice.
A word on laxatives, because they often come into play here. The Cochrane review is filed under the title of laxatives, but what was mainly evaluated was fibre. There can be good reasons for the short term use of a laxative, for example when hard stool keeps tearing a fresh fissure open. Taken on your own over weeks and months, however, it is not a solution, it covers up the question of why the stool is so hard. Which agent makes sense for how long therefore belongs in a medical conversation and under medical guidance, especially in pregnancy and with existing bowel disease.
Step 2: ointments and suppositories, honestly placed
The German S3 guideline puts it soberly: topical preparations are a symptomatic treatment, they may be used for acute symptoms, but they do not replace a targeted therapy. The European guideline adds that for non steroidal anti inflammatory drugs and cortisone in haemorrhoids, scientific data are missing.
I deliberately name no preparations and no application schemes. Two things are important nonetheless. An ointment may dampen the irritation, it does not change the enlarged cushion. And steroid containing agents belong in short, medically guided applications, because this skin can react to permanent treatment with thinning and stretch marks.
For oral vascular agents, the phlebotonics, a Cochrane review with 20 studies and 2344 participants is available. It reports favourable effect estimates for itching, bleeding and overall improvement, but no significant difference for pain (p = 0.06), and the authors name considerable methodological limits.
I deliberately do not give the individual effect figures here, for a simple reason: the German S3 guideline gives diosmin and hesperidin only grade 0 and records that they are not licensed as medicines in Germany. What is sold here are food supplements, and for those I neither may nor want to claim an effect against a disease. In pregnancy and while breastfeeding the data are thinner still, so the question belongs under medical and midwifery guidance there anyway.
Step 3: sclerotherapy and rubber band ligation
Both are outpatient procedures, usually without anaesthesia.
What the guideline and the studies say about them
- Sclerotherapy, that is obliteration
- Recommended at grade 1 to 2 (S3 recommendation 12, grade 0), preferably with the prescription only agent polidocanol, to which the guideline attributes the lowest potential for side effects among the sclerosing agents (recommendation 11). Success rates in most randomised studies 58 to 100 percent, with two outliers at 8 and 22 percent. The complication rate is on average lower than with ligation, but it is not zero: burning and a feeling of pressure for one to two days are common, and rarely there is ulceration at the injection site, allergic reactions and, in individual cases, inflammation in the lesser pelvis. The reported recurrence rates scatter widely and reach up to about 81 percent after as much as four years in the analysed works. That does not mean sclerotherapy achieves nothing: it is a repeatable outpatient procedure with a low complication rate, and it is applied again when needed.
- Rubber band ligation, that is banding
- Treatment of choice at grade 2 (S3 recommendation 16, grade B), also usable at grade 1 and 3 (recommendation 17) and preferable to sclerotherapy at grade 2 to 3 (recommendation 13). From 54 studies with 15,780 people the primary success rate is almost always given as above 90 percent, falling with the size of the tissue. No more than two ligations per session, with some weeks in between. Most important complications: pain when the band is placed too deep, and a delayed bleeding when the band falls off after some days.
With certain blood thinning drugs, neither procedure is performed (S3 recommendation 47, grade A). It never follows from this that you stop such a medication yourself, but that the planning of the procedure follows the medication.
17 British clinics randomised 372 people with grade 2 or 3 to a Doppler guided artery ligation or a rubber band ligation.
After twelve months, 49 percent had a recurrence after rubber band ligation compared with 30 percent after artery ligation (adjusted OR 2.23; p = 0.0005). If a single artery ligation is compared with a repeated rubber band ligation, the rate falls to 37.5 percent and the difference disappears (adjusted OR 1.35; p = 0.20). The band ligation hurt less on day 1 and day 7, serious events occurred more often in the artery ligation group, and it cost 1027 pounds more.
For you that means: if symptoms come back after a ligation, the treatment was not wrongly chosen. The European guideline writes the repetition explicitly into recommendation 3.2.
Brown SR, Tiernan JP, Watson AJM et al. Lancet. 2016;388(10042):356-364. PMID: 27236344 · DOI: 10.1016/S0140-6736(16)30584-0 · HTA report: Health Technol Assess. 2016;20(88):1-150. PMID: 27921992 · DOI: 10.3310/hta20880 [RCT, n=372]Step 4: surgery
In Germany about 1.5 percent of all presumed treatment cases are operated on. The question comes up less often than the tone of some advice pages suggests.
A Cochrane review by Vinod Shanmugam compared rubber band ligation and excisional surgery. It rests on only three studies with 202 people in total, whose methodological quality the authors themselves describe as poor. With that reservation: at grade 3 surgery was superior (RR 1.23; 1.04 to 1.45, from two studies with 116 people), at grade 2 no difference appeared (RR 1.07, from a single study with 32 people, so a very thin basis). Repeat treatments were less frequent after surgery (RR 0.20), but there was more pain (RR 1.94) and more late complications (RR 6.32, with a range of 1.15 to 34.89, so the order of magnitude is uncertain, the direction is not). Satisfaction was similar.
The eTHoS trial randomised 777 people with grade 2 to 4 to a stapled procedure or classic surgery. In the short term the stapler hurt less. Over 24 months, quality of life was higher after classic excision (mean difference -0.073; p = 0.0342). The authors recommend it as the surgical procedure of choice.
For you that means: the procedure that is more comfortable in the short term is not automatically the better one. This question is answered over two years, not over two weeks.
Shanmugam V, Thaha MA, Rabindranath KS et al. Cochrane Database Syst Rev. 2005;(3):CD005034. PMID: 16034963 · DOI: 10.1002/14651858.CD005034.pub2 · Watson AJM, Hudson J, Wood J et al. Lancet. 2016;388(10058):2375-2385. PMID: 27726951 · DOI: 10.1016/S0140-6736(16)31803-7 [RCT, n=777]The German S3 guideline quantifies the complications of classic surgery like this: early bleeding 1.7 percent, urinary retention 0.7 percent, late fissures 1 to 2 percent, narrowing of the anal canal 2 to 9 percent, disturbances of continence 5 to 20 percent, recurrence 3 percent. What matters is what hides behind the second figure: it covers fine continence for the most part, meaning uncontrolled passage of wind or weeping, and only a small share of it concerns solid stool. That is unpleasant and belongs in the consent conversation, but it is not the same as the picture the word incontinence creates in your head. On aftercare: gentle showering instead of modern wound dressings (recommendation 44), no routine antibiotic prophylaxis (recommendation 45, grade A). Both are decisions for the treating team, not instructions to you. An antibiotic in this context is neither started nor stopped on your own, it is decided and accompanied medically.
Holding back is not inactivity here
The German S3 guideline says in recommendation 6 with strong consensus: primarily asymptomatic haemorrhoids should not be treated invasively. I find that well justified, and I am happy to say why.
55.3 percent of people with haemorrhoids have no symptoms. In the same Viennese cohort, quality of life did not differ measurably between the two groups (52.6 versus 53.2; p = 0.7993). A not inconsiderable share of low grade findings becomes symptom free again without treatment, according to the guideline. And every invasive treatment has rare but real serious complications (recommendation 49, grade A).
Fairly added: the SF-12 is a coarse instrument and captures such a local symptom poorly. The number does not devalue your experience. It only explains why a finding without symptoms is not a reason to treat.
What sits in the causal chain, and how much of it is supported
Here it gets uncomfortable. On the development of the condition, the German S3 guideline writes literally that the changes leading to it are insufficiently supported scientifically, that the secured data are sparse and the material often contradictory. A sentence that rarely appears in patient facing texts. That is why I sort the usual suspects by how well they are supported.
The factors, sorted by what stands behind them
- Stool consistency and straining. Plausible and supported by the guideline, but not as clear cut as claimed. Johanson and Sonnenberg analysed four national data sources in 1990: haemorrhoids cluster between 45 and 65 years and at higher socioeconomic status, constipation rises exponentially only after age 65 and at low income. The authors therefore questioned the causal assumption. Constipation remains a factor, but it does not explain the pattern on its own. More on this in the article constipation seen whole.
- Time on the toilet. A cross sectional study from Boston with 125 people before screening colonoscopy: 43 percent had endoscopically visible haemorrhoids, 66 percent used a smartphone there. 37.3 percent of them sat for longer than five minutes per visit, compared with 7.1 percent of the others (p = 0.006). After adjustment for age, sex, body mass index, exercise, straining and fibre, smartphone use on the toilet was associated with a 46 percent raised risk (p = 0.044). The sitting time itself was not accounted for separately in that calculation. Ramprasad C et al. PLoS One. 2025;20(9):e0329983. PMID: 40901789 · DOI: 10.1371/journal.pone.0329983 [Cross sectional study, n=125]. An association, not a cause. It is still the most concrete lever in this article.
- Body weight. In the Viennese cohort, body mass index was an independent risk factor, one point more corresponded to 3.5 percent more risk.
- Connective tissue. Mechanistically plausible via Thomson and Lohsiriwat, human studies with hard endpoints are missing.
- Exercise and drinking volume. The European guideline recommends both and writes at the same time that no systematic reviews or randomised studies were found on this. Expert opinion, low risk and cheap, but not a supported therapy.
Pregnancy and the postpartum period: a case of its own
Hardly any phase of life brings so many anal symptoms, and hardly any is borne so quietly.
A prospective cohort in Ghent followed 94 pregnant women from week 19 to three months after the birth. 68 percent developed anal symptoms, and the most common single symptom was anal pain. Two independent risk factors remained: constipation with OR 6.3 (2.08 to 19.37) and earlier anal symptoms with OR 3.9. Typical were prolapse in the third trimester and thrombosis directly after the birth. Ferdinande K et al. Colorectal Dis. 2018;20(12):1109-1116. PMID: 29972721 · DOI: 10.1111/codi.14324 [Cohort, n=94]
One priority follows from this: whoever keeps an eye on stool consistency during this time is addressing the strongest known risk factor. The German S3 guideline recommends in recommendation 48 that surgery be avoided during pregnancy. Whatever is used in pregnancy and while breastfeeding belongs under medical and midwifery guidance.
The good news: much of it improves in the weeks after the birth. Whatever is still there after three months should be looked at once.
What everyday life can contribute, as directions
No protocol, no quantities. Four directions, each with its evidence strength beside it.
What you have in your own hands
Keep stool soft. Supported for symptoms and bleeding, not for prolapse. The only everyday measure with Cochrane data behind it.
Keep the toilet visit short and leave the phone outside. One cross sectional study plus expert opinion. Low risk, free, plausible: whoever sits for a long time on an open ring surface fills the cushions.
Do not strain and do not force the urge. The German S3 guideline gives changed toilet behaviour recommendation grade 0 and calls the basis sparse itself. Sensible, but not proven.
Clean gently. Water instead of soap, no rubbing, no perfumed wet wipes. Dermatologically justifiable, without randomised studies of its own.
And what about warm sitz baths? An old clinical tradition. I am not aware of a supported advantage over plain showering, and the German S3 guideline explicitly recommends showering for aftercare (recommendation 44). If they do you good, little speaks against them. As a supported treatment I would not sell them.
This here is not a statement from studies, it is an observation from my consultations.
What is underestimated most often are sitting time and tension. Many people sit for ten minutes and strain in waves while doing so, without noticing. If nothing happens after two minutes, the urge is usually not there yet. Get up, come back later. Uncomfortable, and in my view more important than it looks. Whether it achieves more than an ointment I do not know, there are no studies on that. What I describe here is an observation, not a result.
I have no studies with endpoints for this. You now know what rank this observation has.
Why shame is so expensive
Now the part that is medically the simplest and humanly the hardest.
A Romanian group around Adrian Coțe surveyed 185 people on knowledge, stigma and the willingness to seek medical advice.
Only 30.8 percent had ever sought medical advice. The main barriers were shame and the fear of invasive diagnostics. Colonoscopy put off 39.5 percent, the digital rectal examination 38.9 percent. Younger age (p < 0.001) and male sex (p = 0.013) went along with more reluctance.
For you that means: the fear is not directed at the diagnosis, it is directed at the examination. That is exactly where the most can be defused.
Coțe A, Negruț RL, Feder B et al. J Clin Med. 2025;14(15):5361. PMID: 40806983 · DOI: 10.3390/jcm14155361 [Cross sectional survey, n=185]The figure comes from a survey in one country and is not representative. The direction matches what I hear in my consultations.
What the waiting costs can be said in three points. With a thrombosis it is weeks instead of days. In people under 50 with bleeding that has not been investigated it is a delayed diagnosis. And for everyone else it is months or years with a symptom that can often be classified and then addressed in a targeted way, sometimes after the first appointment.
What I still have to say honestly about the evidence
The professional world is divided on this topic too, and that does not come from me, it comes from within it.
Why there is no single right path here
Steven Brown and colleagues searched systematically for haemorrhoid guidelines from 2011 to 2021 and appraised them with the AGREE II instrument. They found nine worldwide. The methodological quality was poor overall, and only a single one was rated as sufficiently high quality. The same published evidence was interpreted contradictorily in different guidelines.
And the situation here at home: the title page of the German S3 short version states that it has not been updated for more than five years and is currently being revised.
This is not ammunition against gastroenterology or coloproctology. Both work with a thin data base, and their restraint has good reasons. It is an invitation not to treat recommendations like laws of nature.
An anal examination takes a few minutes and is, for most people, uncomfortable rather than painful. One exception belongs said out loud: if a fresh fissure, a thrombosis or an abscess is behind it, the examination can hurt. It is then done gently, with an anaesthetic gel or in two steps, and sometimes treatment comes first and the closer look afterwards. Just say so if it hurts. That belongs to the examination and it changes the approach.
The waiting often takes years. You are trading a short discomfort for a long one. In that direction the arithmetic does not pay off.
Common questions about haemorrhoids and anal symptoms
Does everyone really have haemorrhoids, and why do we then speak of a disease?
Yes. Haemorrhoids are arteriovenous cushions in the anal canal that every person has and needs for fine continence. Only when this cushion enlarges, slides downwards and produces symptoms do we speak of haemorrhoidal disease. In an Austrian examination of 976 people, 38.93 percent had a finding, and 55.26 percent of those had no symptoms at all.
I saw bright red blood on the toilet paper. Should I be worried?
Panic is not needed, an examination is. In a systematic review from primary care, the pooled positive predictive value of rectal bleeding for bowel cancer was 8.1 percent from age 50, with a range of 6 to 11 percent. Eight in a hundred is not nothing. The German S3 guideline states that peranal bleeding must be investigated. See the red flag box above.
Can blood at the anus come from bowel cancer even though I am under 50?
It happens. In an analysis of 180 people under 50 with bowel cancer, bleeding was the most common symptom at 59 percent and had often been assigned to haemorrhoids beforehand. 53 percent already had stage 3 or 4, and only 8 percent had a first degree relative with bowel cancer. Young age rules nothing out, see the red flag box above.
How can I tell whether I have an anal fissure or haemorrhoids?
The most important difference is pain. The German S3 guideline records that pain points to other causes, for example fissure, abscess or thrombosis. A fissure cuts during the bowel movement and burns afterwards. Internal haemorrhoids sit above the pain sensitive dentate line and tend to bleed rather than hurt.
I suddenly developed a hard, very painful lump at the anus. What is that?
The pattern most often fits a perianal venous thrombosis, a blood clot in a vein at the anal margin. Typical signs are a sudden onset, a taut bluish lump and pain even without a bowel movement. But this can only be said with certainty at the examination, because an abscess can look exactly the same. If fever, shivering, a swelling that increases over days or a throbbing pain come with it, that belongs to be looked at the same day, and with fever through the emergency department or the German out of hours service on 116 117. In a cohort of 231 people with confirmed thrombosis it took a mean of 24 days to become symptom free with conservative care, and 3.9 days after removal of the clot. Such a lump is never squeezed or cut open by yourself.
What are anal skin tags, and do they have to go?
Anal skin tags are soft flaps of skin at the anal margin. They cannot be pushed back, they do not bleed and they usually do not hurt. They are the most common mix up of all: what people feel as their own haemorrhoids is often a skin tag. A reason to treat arises only when they make cleaning difficult and encourage eczema.
It itches at the anus, especially at night. Is that haemorrhoids?
Sometimes, but often not. Itching at the anus has a broad range of causes, from infections through contact reactions to soaps and wet wipes to underlying anorectal conditions. Anal eczema is frequently a consequence rather than a starting point. A dermatological review warns against months of self treatment with steroid containing combination preparations.
What do grades 1 to 4 mean, and does the grade say anything about my symptoms?
The Goligher classification describes how far the cushion steps outwards. Grade 1 is visible only in the proctoscope, grade 2 comes forward on straining and goes back on its own, grade 3 has to be pushed back, grade 4 lies permanently outside. The German S3 guideline adds that the transitions are fluid and that symptoms need not correlate with size or prolapse.
Do haemorrhoids go away on their own?
At a low grade often yes. The German S3 guideline records that a not inconsiderable share of low grade cases becomes symptom free again without treatment. That is why primarily symptom free haemorrhoids should not be treated invasively. And still: waiting does not replace investigating a bleeding.
After the rubber band ligation it came back. Was the treatment pointless?
Probably not. In the HubBLe trial with 372 participants the recurrence rate after one year was 49 percent after rubber band ligation compared with 30 percent after artery ligation. If a single artery ligation is compared with a repeated band ligation, the rate falls to 37.5 percent and the difference disappears. The ligation is repeated.
What can haemorrhoid ointments do, and what can they not do?
The German S3 guideline classifies topical preparations as symptomatic treatment that may be used for acute symptoms but does not replace a targeted therapy. For non steroidal anti inflammatory drugs and cortisone, scientific data are missing according to the European guideline. An ointment may dampen the irritation, it does not change the enlarged cushion. Weeks of steroid self treatment without a diagnosis risks skin damage.
When does surgery become necessary, and what does it cost me in time and discomfort?
A Cochrane review compared rubber band ligation and surgery, but on the basis of only three studies with 202 people in total, whose methodological quality the authors themselves describe as poor. With that reservation: at grade 3 surgery was superior (RR 1.23), at grade 2 there was no difference (RR 1.07, from a single study with 32 people). Repeat treatments were less frequent after surgery (RR 0.20), but there was more pain (RR 1.94) and more late complications (RR 6.32, range 1.15 to 34.89). The German S3 guideline reports narrowing of the anal canal in 2 to 9 percent and disturbances of continence in 5 to 20 percent, for the most part of fine continence, meaning wind or weeping. Only a small share of it concerns solid stool.
I developed haemorrhoids in pregnancy. Will that go away after the birth?
It often improves clearly after the birth. In a cohort from Ghent with 94 pregnant women, 68 percent developed anal symptoms, and the independent risk factors were constipation (OR 6.3) and earlier anal symptoms (OR 3.9). The German S3 guideline advises avoiding surgery during pregnancy. Whatever is used in this period belongs under medical and midwifery guidance.
Do I really have to see a doctor about anal symptoms, or can I watch it for a while?
You can watch a symptom you already know and that is improving. Blood, a new lump or a new change in bowel habit do not belong in that group. In a Romanian survey with 185 participants, only 30.8 percent had ever sought medical advice. The examination takes a few minutes. The red flag box above tells you what does not wait.
Where this topic connects to the rest of the body
Anal symptoms hang on stool consistency, on the nervous system, on nutrition and sometimes on a blood loss that nobody has noticed.
Fibre myths
Where the number 30 comes from and what it means
Iron deficiency and the gut
When an unnoticed bleeding shows up in the laboratory
Gut brain axis
How tension shapes the pelvic floor
Inflammatory foods
What nutrition contributes to states of irritation
Sleep and the microbiome
The overlooked timekeeper of digestion
Gut reset
The overall concept behind it
Scientific sources
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- Benson AB et al. Anal Carcinoma, Version 2.2023, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2023;21(6):653-677. PMID: 37308125 · DOI: 10.6004/jnccn.2023.0030 [Guideline]
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- Johanson JF, Sonnenberg A. The prevalence of hemorrhoids and chronic constipation. Gastroenterology. 1990;98(2):380-386. PMID: 2295392 · DOI: 10.1016/0016-5085(90)90828-o [Epidemiological registry analysis]
- Ramprasad C et al. Smartphone use on the toilet and hemorrhoid risk. PLoS One. 2025;20(9):e0329983. PMID: 40901789 · DOI: 10.1371/journal.pone.0329983 [Cross sectional study, n=125]
- Grucela A et al. Clinician accuracy in the diagnosis of benign anal pathology. Dis Colon Rectum. 2010;53(1):47-52. PMID: 20010350 · DOI: 10.1007/DCR.0b013e3181bbfc89 [Prospective diagnostic accuracy study, n=198]
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- Myers EA et al. Colorectal cancer in patients under 50. World J Gastroenterol. 2013;19(34):5651-5657. PMID: 24039357 · DOI: 10.3748/wjg.v19.i34.5651 [Cohort, n=180]
- Cohee MW et al. Benign Anorectal Conditions. Am Fam Physician. 2020;101(1):24-33. PMID: 31894930 [Mechanism Review]
- English K et al. Anal squamous cell carcinoma in a patient without significant risk factors. Qatar Med J. 2024;2024(1):7. PMID: 38362253 · DOI: 10.5339/qmj.2024.7 [Case report, single case]
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- Swamiappan M. Anogenital Pruritus: An Overview. J Clin Diagn Res. 2016;10(4):WE01-WE03. PMID: 27190932 · DOI: 10.7860/JCDR/2016/18440.7703 [Mechanism Review]
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- Alonso-Coello P et al. Fiber for the treatment of hemorrhoids complications. Am J Gastroenterol. 2006;101(1):181-188. PMID: 16405552 · DOI: 10.1111/j.1572-0241.2005.00359.x [Systematic Review]
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- Shanmugam V et al. Rubber band ligation versus excisional haemorrhoidectomy. Cochrane Database Syst Rev. 2005;2005(3):CD005034. PMID: 16034963 · DOI: 10.1002/14651858.CD005034.pub2 [Systematic Review]
- Brown SR et al. Haemorrhoidal artery ligation versus rubber band ligation (HubBLe). Lancet. 2016;388(10042):356-364. PMID: 27236344 · DOI: 10.1016/S0140-6736(16)30584-0 [RCT, n=372]
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- Watson AJM et al. Stapled haemorrhoidopexy versus excisional surgery (eTHoS). Lancet. 2016;388(10058):2375-2385. PMID: 27726951 · DOI: 10.1016/S0140-6736(16)31803-7 [RCT, n=777]
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- The causal chain is poorly supported. The German S3 guideline writes itself that the changes leading to the condition are insufficiently supported, that secured data are sparse and the material often contradictory.
- Constipation as a cause is not secured. Johanson and Sonnenberg found completely different age peaks and social distributions. Connective tissue weakness and toilet time are only plausible, or supported by a cross sectional study with 125 people.
- Lifestyle and toilet training are expert opinion. The European guideline writes that no systematic reviews or randomised studies were found on this, the German S3 guideline calls the basis sparse and assigns grade 0.
- Ointments and suppositories are barely studied. The German S3 guideline calls topical preparations a symptomatic treatment that does not replace a targeted therapy, and the European guideline records that data are missing for non steroidal anti inflammatory drugs and cortisone. For sitz baths I am not aware of a supported advantage over showering, and the German S3 guideline recommends showering for aftercare.
- Oral vascular agents show favourable effect estimates with heterogeneous study quality, without a significant effect on pain, with grade 0, and they are not licensed in Germany.
- The recognition studies used photographs, not examinations, and the teaching study included only 36 people. The shame figure comes from a Romanian survey with 185 participants, self reported, not representative.
- The section on anal carcinoma rests on a narrow basis. It draws on an oncological guideline and a single case report. A case report can show that a mix up occurs, it cannot say how often. The Cochrane review on surgery rests on only three studies with 202 people and poor methodological quality.
- The guideline landscape is inconsistent. Of nine haemorrhoid guidelines found worldwide, only one was rated as methodologically sufficient, and the German S3 guideline is currently being revised.
- Deliberately left out. No rule of thumb about blood colour, because it would invite reading bright blood as an all clear. No product names, no dosages, no instructions for self treatment. No effect figures for diosmin and hesperidin, because these agents are not licensed as medicines in Germany and I neither may nor want to claim an effect against a disease for a food supplement. No sentence that suggests postponing a recommended colonoscopy, proctoscopy or procedure, and no advice to change medication on your own. What I describe from my consultations is marked as an observation.